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Sat Nov 9 13:16:53 JST 2002

Can Copper Ions Treat Alzheimer’s Disease?

On 2 April, 2001, these words made headlines on the Japan Financial Times.

Diseased protein cells caused by Alzheimer’s Disease, are now kept under control by copper ions. This was the result of Dr. Sugimoto Naoya’s (from Konan University) success with the introduction of copper ions into protein cells of brains afflicted with Alzheimer’s Disease, in order to keep the disease under check. The introduction of copper into the human body as a form of treatment may be difficult but making medical products based on this concept is believed to be advantageous.

When Alzheimer’s Disease is present, protein molecules which divide easily under normal circumstances, will form clumps within the brain and destroy cells in the nervous system. Dr. Sugimoto has confirmed that after mixing these protein molecules with copper ions, the copper ions attached themselves to the amino acids of these protein molecules and the growth of these diseased protein molecules became retarded.

The experiment was meant to examine the effects of metal ions on DNA and RNA. After observing changes in the molecular structure of protein, Dr. Sugimoto measured the luminous effects on protein when it was exposed to luminous objects. He examined it under an atomic microscope and confirmed the findings.

In the case where copper ions were not present, the protein molecules appeared to settle and fine lines emerged. In contrast, where copper ions were present right from the beginning, this phenomenon was hardly observed. It was concluded that it is possible to treat protein molecules afflicted with Alzheimer’s Disease with copper ions, or rather, it is possible to reverse the molecular structure of protein with copper ions.

What was interesting was that as the settling of the protein molecules continued and its volume increased, the luminous effect dropped dramatically the moment copper ions were introduced. Other metal ions were used in the experiment but copper seemed to have the best effects. The retardation effect of copper ions against protein molecules will give a glimmer of hope not only for Alzheimer’s Disease but also against Prion Disease, Mad-Cow Disease, Creutzfelt-Jacob Disease etc.

Though the experiment is only in its infancy stage, Copper, both an old and new metal all at once, will attempt once more to open up this whole new field of knowledge.



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